By Dave Graham and Alberto Fajardo
MEXICO CITY (Reuters) - The&nbsp;party&nbsp;of&nbsp;Mexican&nbsp;President Andres Manuel Lopez Obrador was set to&nbsp;win&nbsp;a major opposition bastion in a&nbsp;state&nbsp;election&nbsp;on Sunday, preliminary results showed, giving the country's leader a boost as he seeks to pave the way for a successor next year.
In the&nbsp;State&nbsp;of Mexico gubernatorial race, Lopez Obrador's leftist National Regeneration Movement (MORENA) was expected to&nbsp;win&nbsp;52.1 to 54.2% of the vote, while the candidate running for an opposition alliance was forecast to garner 43.0 to 45.2%, the&nbsp;state's electoral institute (IEEM) estimated.
The most populous region of the country, the&nbsp;State&nbsp;of Mexico surrounds much of the capital and has been an economic and electoral bulwark of the centrist Institutional Revolutionary&nbsp;Party&nbsp;(PRI), which has governed there since 1929.
"It's been 100 long years of corruption and neglect, but times change," MORENA's candidate Delfina Gomez told cheering supporters after claiming victory.
Gomez would be the first woman to govern the&nbsp;state, and victory would add the&nbsp;state&nbsp;to the 21 regional governments MORENA already controls, two-thirds of the total.
Her forecast margin of victory would be slightly narrower than some leading pollsters had predicted.
With some 42% of the vote counted, Gomez had 53.5% support and del Moral 43.6%, IEEM's preliminary figures showed.
Interest in the&nbsp;election&nbsp;was also tepid. At somewhere between 48% and 50%, turnout was forecast by IEEM to be some 3-4 percentage points lower than at the previous&nbsp;election.
On a recent visit to the&nbsp;state, many of the residents Reuters met were not enthusiastic about voting.
Lopez Obrador routed the PRI to&nbsp;win&nbsp;the presidency in 2018, and MORENA has since absorbed most of the once-dominant&nbsp;party's strongholds, alongside many of its politicians.
Still, in a separate&nbsp;election, early results showed the PRI was poised to easily maintain the northern border&nbsp;state&nbsp;of Coahuila, where MORENA was riven by&nbsp;party&nbsp;infighting.
SUCCESSION
The votes comes a year before Mexico's next presidential&nbsp;election, with polls indicating MORENA will be hard to beat.
Decades of one-party&nbsp;rule made the PRI a byword for corruption among many&nbsp;Mexicans, and it has struggled to compete with MORENA's message that it represents a vote for change.
Jobita Pena, a 67-year-old homemaker in the municipality of Tlalnepantla on Mexico City's northern edge, said she wanted MORENA to bring change to the&nbsp;state&nbsp;of 17 million people.
"For a better Mexico, for new projects, which really are delivered this time," Pena said.
Gomez vowed to give a fresh start to the&nbsp;state&nbsp;and to improve security, mindful of widespread concern over violence.
Her opponent, Alejandra del Moral, a PRI politician heading the opposition ticket, said her&nbsp;party&nbsp;had learned from its mistakes, and that she represented a broader alternative.
Lopez Obrador has dominated political life since taking office in December 2018, and his popularity, holding firm around 60%, has helped make MORENA a formidable electoral machine. Under&nbsp;Mexican&nbsp;law, presidents may serve only one six-year term.
Nevertheless, his abrasive style and uncompromising agenda, which has pitted the&nbsp;state&nbsp;against private enterprise, and fueled conflict with curbs on that power such as the judiciary, have polarized voters.
Mexico City's mayor, Claudia Sheinbaum, has had a slight edge in most polling for the race to be MORENA's presidential candidate, closely followed by Foreign Minister Marcelo Ebrard.
Sheinbaum, like Gomez, is closely identified with Lopez Obrador and his policies.
Some analysts say a decisive MORENA victory in the&nbsp;state&nbsp;augurs well for her hopes for the presidential ticket.
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(Reporting by Dave Graham and Alberto Fajardo; Editing by Aurora Ellis, Will Dunham, Lisa Shumaker and Gerry Doyle)

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Mexican president's party to win key state in election